Basic information

Vitamin B₆, or pyridoxine, is composed of a group of three compounds: pyridoxine, pyridoxal and pyridoxamine, which exist in its phosphorylated form in the body. As a water-soluble vitamin, it acts as a component of some coenzymes in human bodies responsible for a great many metabolic reactions.

Product Features

It is involved in nearly 100 enzymatic reactions in the form of pyridoxal phosphate (PLP), most of which are related to amino acid metabolism, including transamination, decarboxylation, side chain cleavage, dehydration and sulfuration. These biochemical functions are involved in many aspects. It is involved in the synthesis and catabolism of proteins and participates in all amino acid metabolism. For example, it plays a role in the metabolism of heme and the synthesis of niacin by tryptophan. It takes part in the gluconeogenesis and UFA metabolism, and is related to the metabolism of glycogen, sphingomyelin, and steroids.It is engaged in the synthesis of some neurotransmitters, including 5- HT, taurine, dopamine, norepinephrine and γ-aminobutyric acid.It participates in the metabolism of one-carbon unit, VB12 and folate. Megaloblastic anemia can occur in the metabolic disorder of VB6. It is required in the synthesis of nucleic acid and DNA. Inadequate supply of VB6 can lead to the damage of DNA in its synthesis, which plays a vital role for maintaining competent immune function. Vitamin B6 is closely related to vitamin B2. Vitamin B6 deficiency is often goes along with vitamin B2 deficiency.It contributes to the transformation of homocysteine to methionine and the mitigation of risk of chronic diseases. Mild hyperhomocysteinemia is considered as a hidden risk factor for vascular diseases, and the intervention of vitamin B6 can reduce the plasma homocysteine content.